2025
RNA origami nanotubes push the boundaries of confinement. Kosiorek S, De Franceschi N. Nature Nanotechnology. 2025 Mar 17.
Interaction hierarchy among Cdv proteins drives recruitment to membrane necks. De Franceschi N, Blanch-Jover A and Dekker C. eLife14:RP104226. 2025 Jan 16.
2024
Engineering ssRNA tile filaments for (dis)assembly and membrane binding. De Franceschi N, Hoogenberg B, Katan A and Dekker C. Nanoscale. 2024 Feb 29;16(9):4890-4899.
Dynamin A as a one-component division machinery for synthetic cells. De Franceschi N, Barth R, Meindlhumer S, Fragasso A and Dekker C. Nature Nanotechnology. 2024 Jan;19(1):70-76.
2023
Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage. Azad K, Guilligay D, Boscheron C, Maity S, De Franceschi N, Sulbaran G, Effantin G, Wang H, Kleman JP, Bassereau P, Schoehn G, Roos WH, Desfosses A, Weissenhorn W. Nat Struct Mol Biol. 2023 Jan;30(1):81-90.
2022
The archaeal division protein CdvB1 assembles into polymers that are depolymerized by CdvC. Blanch-Jover A, De Franceschi N, Fenel D, Weissenhorn W, Dekker K. FEBS Lett. 2022 Apr;596(7):958-969.
A Synthetic Membrane Shaper for controlled liposome deformation. De Franceschi N, Pezeshkian W, Fragasso A, Bruininks B, Tsai S, Marrink SJ and Dekker C. ACS Nano. 2022 Nov 28;17(2):966–78.
2021
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules. Fragasso A*, De Franceschi N*, Stömmer P*, van der Sluis E, Dietz H, Dekker C. ACS Nano. 2021 Jun 25;15(8):12768–79.
Optimized cDICE for Efficient Reconstitution of Biological Systems in Giant Unilamellar Vesicles. Van de Cauter L, Fanalista F, van Buren L, De Franceschi N, Godino E, Bouw S, Danelon C, Dekker C, Koenderink GH, Ganzinger KA. ACS Synth Biol. 2021 Jul 16;10(7):1690-1702 .
Towards a synthetic cell cycle. Olivi L, Berger M, Creyghton RNP, De Franceschi N, Dekker C, Mulder BM, Claassens NJ, Ten Wolde PR, van der Oost J. Nature Communication. 2021 Jul 26;12(1):4531.
The ESCRT-III Isoforms CHMP2A And CHMP2B Display Different Effects On Membranes Upon Polymerization. Alqabandi M*, De Franceschi N*, Miguet N, Maity S, Bally M, Roos WH, Weissenhorn W, Bassereau P, Mangenot S. BMC Biol. 2021 Apr 8;19(1):66.
2020
Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation. Bertin A*, De Franceschi N*, de la Mora E, Maity S, Alqabandi M, Miguet N, di Cicco A, Roos WH, Mangenot S, Weissenhorn W, Bassereau P. Nature Communications. 2020;11(1):2663.
MASTL promotes cell contractility and motility through kinase-independent signaling. Taskinen ME, Närvä E, Conway JRW, Hinojosa LS, Lilla S, Mai A, De Franceschi N, Elo LL, Grosse R, Zanivan S, Norman JC, Ivaska J. J Cell Biol. 2020;219(6):e201906204.
2019
Dynamic and Sequential Protein Reconstitution on Negatively Curved Membranes by Giant Vesicles Fusion. De Franceschi N, Alqabandi M, Weissenhorn W, Bassereau P. (2019). Bio-protocol 9(13): e3294.
2018
ProLIF - quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes. De Franceschi N*, Miihkinen M*, Hamidi H, Alanko J, Mai A, Picas L, Guzmán C, Lévy D, Mattjus P, Goult BT, Goud B, Ivaska J. J Cell Sci. 2018;132(4):jcs214270.
The ESCRT protein CHMP2B acts as a diffusion barrier on reconstituted membrane necks. De Franceschi N, Alqabandi M, Miguet N, Caillat C, Mangenot S, Weissenhorn W, Bassereau P. J Cell Sci. 2018;132(4):jcs217968.
First person. De Franceschi N. J Cell Sci. 2018 (interview).
2017
Integrin beta 1 inhibition alleviates the chronic hyperproliferative dermatitis phenotype of SHARPIN-deficient mice. Peuhu E, Salomaa SI, De Franceschi N, Potter CS, Sundberg JP, Pouwels J. PLoS One. 2017;12(10):e0186628.
SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Lilja J, Zacharchenko T, Georgiadou M, Jacquemet G, De Franceschi N, Peuhu E, Hamidi H, Pouwels J, Martens V, Nia FH, Beifuss M, Boeckers T, Kreienkamp HJ, Barsukov IL, Ivaska J. Nature Cell Biology. 2017;19(4):292-305.
SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. Peuhu E, Kaukonen R, Lerche M, Saari M, Guzmán C, Rantakari P, De Franceschi N, Wärri A, Georgiadou M, Jacquemet G, Mattila E, Virtakoivu R, Liu Y, Attieh Y, Silva KA, Betz T, Sundberg JP, Salmi M, Deugnier MA, Eliceiri KW, Ivaska J. EMBO J. 2017;36(2):165-182.
2016
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventelä S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen PL, Joensuu H, Grenman R, Ivaska J. Nature Communications. 2016;7:12237
Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2. De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel AG, Wilson TA, Pouwels J, Montagnac G, Owen DJ, Ivaska J. Nature Structural & Molecular Biology. 2016;23(2):172-179.
2015
Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling. De Franceschi N, Peuhu E, Parsons M, Rissanen S, Vattulainen I, Salmi M, Ivaska J, Pouwels J. PLoS One. 2015;10(11):e0143423.
Integrin bondage: filamin takes control. De Franceschi N, Ivaska J. Nature Structural & Molecular Biology. 2015;22(5):355-357.
Vimentin-ERK Signaling Uncouples Slug Gene Regulatory Function. Virtakoivu R, Mai A, Mattila E, De Franceschi N, Imanishi SY, Corthals G, Kaukonen R, Saari M, Cheng F, Torvaldson E, Kosma VM, Mannermaa A, Muharram G, Gilles C, Eriksson J, Soini Y, Lorens JB, Ivaska J. Cancer Res. 2015;75(11):2349-2362.
Integrin traffic - the update. De Franceschi N, Hamidi H, Alanko J, Sahgal P, Ivaska J. J Cell Sci. 2015;128(5):839-852.
2014
Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells. Muharram G, Sahgal P, Korpela T, De Franceschi N, Kaukonen R, Clark K, Tulasne D, Carpén O, Ivaska J. Developmental Cell. 2014;29(5):629-630.
Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery. De Franceschi N, Wild K, Schlacht A, Dacks JB, Sinning I, Filippini F. Traffic. 2014;15(1):104-121.
2013
SHARPIN regulates uropod detachment in migrating lymphocytes. Pouwels J*, De Franceschi N*, Rantakari P, Auvinen K, Karikoski M, Mattila E, Potter C, Sundberg JP, Hogg N, Gahmberg CG, Salmi M, Ivaska J. Cell Reports. 2013;5(3):619-628.
A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin. Hämälistö S, Pouwels J, De Franceschi N, Saari M, Ivarsson Y, Zimmermann P, Brech A, Stenmark H, Ivaska J. PLoS One. 2013;8(8):e70696.
Integrin inactivators: balancing cellular functions in vitro and in vivo Bouvard D, Pouwels J, De Franceschi N, Ivaska J.. Nat Rev Mol Cell Biol. 2013;14(7):430-442.
2012
Improved real-time PCR assay for detection and quantification of all 54 known types of human adenoviruses in clinical samples. Bil-Lula I, De Franceschi N, Pawlik K, Woźniak M. Med Sci Monit. 2012;18(6):BR221-BR228.
Bioinformatic and mutational analysis of channelrhodopsin-2 protein cation-conducting pathway. Plazzo AP*, De Franceschi N*, Da Broi F, Zonta F, Sanasi MF, Filippini F, Mongillo M. J Biol Chem. 2012;287(7):4818-4825.
2011
Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms. Vacca M, Albania L, Della Ragione F, Carpi A, Rossi V, Strazzullo M, De Franceschi N, Rossetto O, Filippini F, D'Esposito M. BMC Mol Biol. 2011;12:26. Interview.